Office for People With Developmental Disabilities

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Neurophysiological Development Laboratory

07/11/12

Bernard Z. Karmel, PhD, Head

[email protected]

The very early organization and development of the infant’s brain and the subsequent behavior that emerges enable the infant to process information about the world and provide the basis for all future action, intelligence, and thought. The Neurophysiological Development Laboratory is devoted to understanding how this neurofunctional organization is achieved and to developing and implementing procedures to improve the diagnosis, prevention and treatment of developmental disabilities, including autism, cerebral palsy, and Down syndrome.

We study children longitudinally from birth to 8 years, concentrating on electrophysiological, neurostructural, and psychometric methods. We use complex mathematical models (individual growth curve analyses) and computer systems (deep database structure) based on early brain organization, to more accurately predict cognitive and sensory-motor organization. Many of these studies involve invaluable video records of very early behavior that can be examined retrospectively for clues to the origins of later cognitive and motor disabilities.

Our research is fundamentally multidisciplinary and is conducted in close collaboration with the Neurobehavioral Development Laboratory in IBR’s Department of Infant Development and the Autism Treatment Research Laboratory in the Department of Psychology; and IBR’s George A. Jervis Clinic